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Walter Gilbert

Walter Gilbert (born March 21, 1932) is an Americanphysicist, biochemist, molecular biology pioneer, and Nobel laureate. He helped develop DNAsequence analysis.

Biography

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Gilbert was born in Boston, Massachusetts, on March 21, 1932.[1] Gilbert attended Harvard University for undergraduate and graduate studies, earning a first degree in chemistry and physics in 1953 and a master's degree in physics in 1954.[1]

Gilbert's doctoral work was done at the University of Cambridge, where he earned his PhD in mathematics under the mentorship of Nobel laureate Abdus Salam in 1957.[1]

Gilbert returned to Harvard in 1957 and promoted in 1968 to professor of biochemistry.[1] In 1969, Gilbert was given Harvard's Ledlie Prize.[1] In 1972, Gilbert was named American Cancer Society Professor of Molecular Biology.[1]

He is a co-founder of the biotech start-up companies Biogen and Myriad Genetics. Gilbert is currently the chairman of the Harvard Society of Fellows.

Research findings

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Walter Gilbert is a Nobel Prize-winning scientist who started his career in theoretical physics before moving to molecular biology, working hard to compensate for his lack of formal training in the field. Walter has made many major discoveries concerning gene control and nucleic acids and is best known for devising one of the first methods of DNA sequencing.

Knowledge of DNA sequences is instrumental for basic biological research as well as applied fields such as diagnostic, biotechnology and virology. In the mid-1970s, Walter and Allan Maxam found a way to determine the precise sequence of nucleotide ‘links’ in the chainlike molecules of nucleic acids, using radioactive labelling. The resulting Maxam–Gilbert sequencing proved popular as it offered certain advantages over the Sanger dideoxynucleotide method.

Walter was awarded the 1980 Nobel Prize in Chemistry for his pioneering work in nucleic acids, which he shared with Frederick Sanger and Paul Berg. He has since been involved with the Human Genome Project, an international scientific research project to compile a comple

Walter Gilbert

American biochemist

For other people named Walter Gilbert, see Walter Gilbert (disambiguation).

Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate.[3][4][5]

Education and early life

Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, into a Jewish family,[6] the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist.[4][7]

When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21.[8]

He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954.

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