I am a retired teacher and firearms enthusiast. I like old and unusal stuff. Dont mess with much that is Post WWII. I am primarily a researcher and guns are my favorite topic. I am not a dealer but I do help people when they get dad's guns and don't know what to do. Thus the reason I wound up here.
The Peterlongo Cape Gun appeared on my doorstep a week or so ago. I found out some stuff. It is black powder proofed. It has good bores and a tight action. It has double set triggers. The shotgun is 16 ga. chamber for 2 & 5/8. The rifle is 8mm X 72 Sauer. It is well used, most of metal finish is gone with a bit of plumb bluing scattered about and small amounts of faint case
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StrainFLAIR: strain-level profiling of metagenomic samples using variation graphs
Introduction
The use of reference genomes has shaped the way genomics studies are currently conducted. Reference genomes are particularly useful for reference guided genomic assembly, variant calling or mapping sequencing reads. For the latter, they provide a unique coordinate system to locate variants, allowing to work on the same reference and easily share information. However, the usage of reference genomes represented as flat sequences reaches some limits (Ballouz, Dobin & Gillis, 2019). One sequence chosen as the reference among other homologous sequences does not capture the whole genomic variability. Hence, reads from non-reference alleles may be mis-mapped or not mapped at all. Secondly, with the increasing availability of new genomes, several sequences can be used as multiple references. However, close genomes (typically genomes of strains of the same species) show a high sequence similarity. The mapping of sequencing reads results in mis-mapped reads or ambiguous alignments generat
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