Frederick griffith contribution to dna
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Frederick Griffith
British bacteriologist (1877–1941)
For other people named Frederick Griffith, see Frederick Griffith (disambiguation).
Frederick Griffith (1877–1941) was a British bacteriologist whose focus was the epidemiology and pathology of bacterial pneumonia. In January 1928 he reported what is now known as Griffith's experiment, the first widely accepted demonstrations of bacterial transformation, whereby a bacterium distinctly changes its form and function.[2]
He showed that Streptococcus pneumoniae, implicated in many cases of lobar pneumonia,[3] could transform from one strain into a different strain. The observation was attributed to an unidentified underlying principle,[2] later known in the Avery laboratory as the "transforming principle" (abbreviated as T. P.)[4] and identified as DNA.[5] America's leading pneumococcal researcher, Oswald T. Avery, speculated that Griffith had failed to apply adequate controls.[6] A cautious and thorough researcher, and a reticent individual, Griffith's tendency
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Frederick Griffith
Frederick Griffith (ur. 1877 lub 1881, zm. 1941 w Londynie) – brytyjski lekarz i naukowiec, który w 1928 r. jako pierwszy zbadał i opisał zjawisko transformacji DNA.
Urodził się w Hale i studiował na Liverpool University, gdzie zajmował się genetyką. Na początku swojej kariery zawodowej pracował w szpitalu Liverpool Royal Infirmary, Thompson Yates Laboratory i w Królewskiej Radzie do Zwalczania Gruźlicy (Royal Commission on Tuberculosis).
Zginął podczas pracy w laboratorium w czasie jednego z nalotów na Londyn w czasie drugiej wojny światowej.
Eksperyment Griffitha
[edytuj | edytuj kod]Frederick Griffith zajmował się badaniami nad szczepionką przeciw zapaleniu płuc, na które dziesięć lat wcześniej umierały setki tysięcy chorych podczas epidemii grypy "hiszpanki".
Badał dwa szczepybakteriiPneumococcus: szczep S, które wytwarzały polisacharydową otoczkę i były zjadliwe oraz szczep R, które bez otoczki były bezbronne wobec układu immunologicznego organizmu. Wirulentne bakterie szczepu S po zabiciu przez podgrzanie i wstrzyknięciu m
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Frederick Griffith facts for kids
Quick facts for kids Frederick Griffith | |
|---|---|
| Born | 1877 (1877) Prescot, England |
| Died | 1941 (1942) (aged 63–64) London, England |
| Education | Liverpool University |
| Occupation | physician, pathologist, bacteriologist |
| Known for | discovery of pneumococcal transformation |
| Scientific career | |
| Institutions | Ministry of Health Pathological Laboratory, Liverpool Royal Infirmary |
Frederick Griffith (1877–1941) was a British bacteriologist whose focus was the epidemiology and pathology of bacterial pneumonia. In January 1928 he reported what is now known as Griffith's Experiment, the first widely accepted demonstrations of bacterial transformation, whereby a bacterium distinctly changes its form and function.
He showed that Streptococcus pneumoniae, implicated in many cases of lobar pneumonia, could transform from one strain into a different strain. The observation was attributed to an unidentified underlying principle, later known in the Avery laboratory as the "transforming principle" (abbreviated as T. P.) and identified a
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